Agnieszka Irena Tudek, PhD

Postdoc

(+48) 22 592 2030  Room no. 030

 

Involved in: RNA biology

Academic and Research Career:

Oct. 2018 – present – Post-Doctoral position in Prof. Andrzej Dziembowski Laboratory of RNA Biology and Functional Genomics, Institute of Biochemistry and Biophysics Polish Academy of Sciences.

Jun. 2014- Aug. 2018 – Post-Doctoral position in Prof. Torben Heick Jensen group,
Department of Molecular Biology and Genetics, Aarhus University, Denmark.

Dec. 2010 – Mar. 2014 – PhD studies, Paris-Sud (11) University, France. Advised by Prof. Domenico Libri, Centre de Genetique Moleculaire, Gif-sur-Yvette, France.

Oct. 2008 – Sept. 2010 – Master studies at Warsaw University, Poland. Master internship with Prof. D. Bartosik at Laboratory of Bacterial Mobile Elements, Institute of Microbiology, Warsaw University, Poland.

25 Feb. – 25 Jun. 2010 – Erasmus student exchange program in Paris-Sud (11) University, Orsay, France. Internship under the supervision of PhD Tommaso Villa from the group of Prof. D. Libri. Laboratory of Nuclear RNA Metabolism, CGM, CNRS Gif-sur-Yvette, France.
03 Aug. – 30 Sep. 2009 – summer training in Prof. Arne Klungland group. Laboratory for Genome Repair and Regulation, Centre for Molecular Biology and Neuroscience, Oslo University Hospital (Rikshospitalet), Norway.

Oct. 2005 – Sept 2008 – Bachelor studies at Warsaw University, Poland. Bachelor internship with Prof. D. Bartosik at Laboratory of Bacterial Mobile Elements, Institute of Microbiology, Warsaw University, Poland.

Publications:

Escaping nuclear decay: the significance of mRNA export for gene expression.
Tudek A, Schmid M, Jensen TH.
Curr Genet. 2019 Apr;65(2):473-476.

Preparation of RNA 3′ End Sequencing Libraries of Total and 4-thiouracil Labeled RNA for Simultaneous Measurement of Transcription, RNA Synthesis and Decay in S. cerevisiae.
Schmid M., Tudek A., Jensen T. H.
Bio Protoc. 2019 Mar 20;9(6).

The multitasking polyA tail: nuclear RNA maturation, degradation and export.
Tudek A, Lloret-Llinares M, Jensen TH.
Philos Trans R Soc Lond B Biol Sci. 2018 Nov 5;373(1762).

A Nuclear Export Block Triggers the Decay of Newly Synthesized Polyadenylated RNA.
Tudek A, Schmid M, Makaras M, Barrass JD, Beggs JD, Jensen TH.
Cell Rep. 2018 Aug 28;24(9):2457-2467.e7.

Simultaneous Measurement of Transcriptional and Post-transcriptional Parameters by 3′ End RNA-Seq.
Schmid M, Tudek A, Jensen TH.
Cell Rep. 2018 Aug 28;24(9):2468-2478.e4.

Lifestyle-determining extrachromosomal replicon pAMV1 and its contribution to the carbon metabolism of the methylotrophic bacterium Paracoccus aminovorans JCM 7685.
Czarnecki J, Dziewit L, Puzyna M, Prochwicz E, Tudek A, Wibberg D, Schlüter A, Pühler A, Bartosik D.
Environ Microbiol. 2017 Nov;19(11):4536-4550.

Nuclear Decay Factors Crack Up mRNA.
Tudek A, Schmid M, Jensen TH.
Mol Cell. 2017 Mar 2;65(5):775-776.

Lipid peroxidation in face of DNA damage, DNA repair and other cellular processes.
Tudek B, Zdżalik-Bielecka D, Tudek A, Kosicki K, Fabisiewicz A, Speina E.
Free Radic Biol Med. 2017 Jun;107:77-89.

Non-coding transcription by RNA polymerase II in yeast: Hasard or nécessité?
Tudek A, Candelli T, Libri D.
Biochimie. 2015 Oct;117:28-36.

Molecular basis for coordinating transcription termination with noncoding RNA degradation.
Tudek A. 1, O. Porrua 1 , T. Kabzinski 1 , M. Lidschreiber, K. Kubicek, A. Fortova, F. Lacroute, S. Vanacova, P. Cramer, R. Stefl, D. Libri.
Mol Cell. 2014 Aug 7;55(3):467-81.
*1 equal contribution

The role of Ctk1 kinase in termination of small non-coding RNAs.
Lenstra T. L.1, Tudek A.1, Clauder S., Xu Z., Pachis S. T., van Leenen D., Kemmeren P., Steinmetz L. M., Libri D. 2, Holstege F. C. 2.
PLoS One. 2013 Dec 4;8(12):e80495.
*1 equal contribution, 2 equal contribution

Insights into the transposable mobilome of Paracoccus spp. (Alphaproteobacteria).
Dziewit L., J. Baj, M. Szuplewska, A. Maj, M. Tabin, A. Czyzkowska, G. Skrzypczyk, M. Adamczuk, T. Sitarek, P. Stawinski, A. Tudek, K. Wanasz, E. Wardal, E. Piechucka, D. Bartosik.
PLoS One. 2012;7(2):e32277.

Conference communications:

Tudek A., Schmid M., Barrass D., Beggs J., Jensen T. H. . ‘Escape from rapid nuclear mRNA decay in the yeast Saccharomyces cerevisiae depends on Nab2 and Mex67.’ ‘The complex life of mRNA’ – EMBO conference 5-8 Oct. 2016, Heidelberg, Germany. Poster.

Tudek A., Schmid M., Barrass D., Beggs J., Jensen T. H. . ‘Escape from rapid nuclear mRNA decay in the yeast Saccharomyces cerevisiae depends on Nab2 and Mex67’. ‘The complex life of mRNA’ – EMBO conference 5-8 Oct. 2016, Heidelberg, Germany. TERM 2017 conference 26-28th Apr. 2017. Sant Feliu de Guixols, Spain. Oral presentation.

Tudek A., Porrua O., Kabzinski T., Lidschreiber M., Kubicek K., Lacroute F., Fortova A., Vanacova S., Cramer P., Stefl R., Libri D. ‘A novel role for the CTD-interacting domain (CID) of Nrd1p in orchestrating transcription termination and RNA degradation.’ ‘Eukaryotic RNA Turnover: From Structural Insights to Diseases’ – EMBO conference 21-24 Apr. 2013, IGBMC, Strasbourg, France. Poster.

Tudek A., Porrua O., Kabzinski T., Lidschreiber M., Kubicek K., Lacroute F., Fortova A., Vanacova S., Cramer P., Stefl R., Libri D. ‘A novel role for the CTD-interacting domain (CID) of Nrd1p in orchestrating transcription termination and RNA degradation.’ TERM conference, 22-24 May 2013, Sant Feliu de Guixols, Spain. Oral presentation.

Dziewit L., D. Wibberg, J. Czarnecki, A. Tudek, A. Schlüter, A. Pühler and D. Bartosik. Insights into the plasmidome of Paracoccus aminophilus JCM 7686 and Paracoccus aminovorans JCM 7685 – methylotrophic strains degrading toxic compounds. International Plasmid Biology